The advantages and characteristics of the chemiluminescence reagent acridine ester NSP-DMAE-NHS 194357-64-7

In the current booming development of in vitro diagnostic technology, chemiluminescence analysis method stands out among many detection methods due to its excellent performance, and its application proportion continues to rise. Among them, acridine ester NSP-DMAE-NHS, as a commonly used chemiluminescence reagent, has shown excellent performance in terms of shipment volume and experimental feedback due to its unique advantages, and is widely used in important fields such as environmental monitoring, clinical analysis, and biochemistry.

1, The luminous system is simple and efficient, without the need for catalyst assistance

The luminescence system of acridine ester NSP-DMAE-NHS has significant advantages, with a simple and direct reaction process that does not require catalyst involvement. In alkaline environments, acridine ester molecules are attacked by hydrogen peroxide, generating unstable ethylene oxide, which rapidly decomposes into carbon dioxide and N-methyl ketone in an electronically excited state. When the substance returns to its ground state, it will release light with a wavelength of 430nm. This process does not require enhancers, effectively reducing background luminescence, not only improving detection sensitivity, but also reducing the interference of external factors on the detection results, providing strong guarantees for accurate detection.

Acridine ester NSP-DMAE-NHS powder

2, Excellent luminous performance, with both intensity and efficiency

Acridine ester NSP-DMAE-NHS exhibits fast and strong chemiluminescence, which is unique in the field of chemiluminescence immunoassay. After only 0.4 seconds of adding the initiator, its chemiluminescence intensity can reach its peak, with a half-life of 0.9 seconds. The luminescence intensity is usually five times or even more than that of luminol. This efficient luminescent performance makes the detection process faster, enabling accurate detection results to be obtained in a short period of time, greatly improving detection efficiency and meeting the urgent need for rapid detection in clinical and scientific research.

3, Less interference factors, fully demonstrating the advantage of signal-to-noise ratio

In depth analysis of the luminescence mechanism reveals that the acridine ester NSP-DMAE-NHS luminescence system has unique advantages. In the luminescent reaction, the non luminescent substituent portion connected to the acridine ring separates from the acridine ring before forming an electron excited intermediate and does not participate in the luminescent process. This separation mechanism ensures that the luminescence efficiency is not significantly affected by the substituent structure, effectively reducing interference factors and lowering the background signal, thereby significantly improving the signal-to-noise ratio. A high signal-to-noise ratio means that the detection results are clearer and more accurate, which can better eliminate the interference of false positives and false negatives and provide reliable basis for the diagnosis and treatment of diseases.

4, Small molecular weight, stable connection and no impact on reactivity

The small molecular weight of acridine ester NSP-DMAE-NHS gives it a unique advantage in biological molecular labeling. It can easily and firmly connect with proteins through chemical bonds, with minimal impact on the conformation of the bound antibody, ensuring that the antibody maintains good reactivity in subsequent reactions. In immunoassays, this stable connection and good reactivity can improve the specificity and accuracy of detection.

Product packaging

Hubei Xindesheng Material Technology Co., Ltd., as an advantageous manufacturer of luminescent reagents, has a history of nearly 20 years since its establishment in 2005. With rich research and development experience, it currently sells luminescent reagents with different functional groups such as acridine ester NSP-DMAE-NHS, acridine ester NSP-SA, and acridine ester NSP-SA-NHS. Desheng has professional laboratories and technicians who can provide customized services according to customer requirements. It is your trusted supplier of chemiluminescence reagents. If you have any related procurement needs in the near future, please feel free to contact me!